Effectiveness of Conservative Treatment without Early Colonoscopy in Patients with Colonic Diverticular Hemorrhage
Table 3
Factors associated with urgent hemostasis.
Conservative treatment (n = 137)
Urgent hemostasis (n = 5)
-value
Age (years, mean ± SD)
71.6 ± 12.8
74.2 ± 11.5
0.652
Sex (male)
84 (61.3%)
4 (80.0%)
0.650
Previous history of diverticular hemorrhage
36 (26.3%)
2 (40.0%)
0.610
Patient on dialysis
11 (8.3%)
0 (0%)
0.999
Patient with cirrhosis
3 (2.2%)
0 (0%)
0.999
Medications
Antithrombotic (total)
53 (38.9%)
3 (60.0%)
0.383
Aspirin
35 (25.5%)
2 (40.0%)
0.605
Thienopyridine derivative
16 (11.7%)
1 (20.0%)
0.477
Dual antiplatelet therapy
9 (6.6%)
1 (20.0%)
0.310
Anticoagulants
21 (15.3%)
2 (40.0%)
0.189
NSAIDs
13 (9.5%)
1 (20.0%)
0.410
Systolic blood pressure <90 (mmHg)
11 (8.3%)
5 (100%)
<0.0001
Heart rate (bpm, mean ± SD)
87.0 ± 20.4
74.2 ± 22.8
0.184
Loss of consciousness
17 (12.4%)
0 (0%)
0.999
Extravasation on CECT
13 (14.0%)
5 (100%)
0.0001
Localization of diverticulum (right-sided/left-sided/bilateral)
34/14/89
4/0/1
0.004
Laboratory data
Hemoglobin level (g/dL, mean ± SD)
10.5 ± 2.5
10.9 ± 3.4
0.696
WBC count (×103/mm3, mean ± SD)
8.1 ± 2.9
8.1 ± 4.0
0.988
Platelet count (×104/mm3, mean ± SD)
20.5 ± 6.2
18.9 ± 2.0
0.584
UN/Cre ratio (mean ± SD)
23.1 ± 10.5
19.1 ± 3.4
0.390
Albumin level (g/dL, mean ± SD)
3.5 ± 0.5
3.2 ± 0.5
0.211
PT-INR (mean ± SD)
1.2 ± 0.7
1.5 ± 0.6
0.429
SD, standard deviation; NSAIDs, nonsteroidal anti-inflammatory drugs; CECT, contrast-enhanced computed tomography; WBC, white blood cells; UN/Cre, urea nitrogen/creatinine; PT-INR, international normalized ratio of prothrombin time. CECT was performed in ninety-three patients in the conservative treatment group.