Review Article

Comparison of the Effects of TIPS versus BRTO on Bleeding Gastric Varices: A Meta-Analysis

Table 2

Characteristics of the included RCT and cohort studies.

Included studiesCountryDesignSample sizeWomen, n (%)Mean ageFollow-upTraits of patientsType of TIPS stentsOutcomes
TotalTIPSBRTOTIPSBRTO

Gimm et al. [27]KoreaCohort1761915737 (21)59.454.45 yearsGV bleedingCoveredIM, RB, C, OS
Kim et al. [28]KoreaCohort52272524 (46)58.059.01 yearGV bleeding (isolated GV)CoveredTS, C, MELD score, IM, RB, OS
Lee et al. [29]KoreaCohort142479527 (19)55.659.43 yearsGV bleedingCoveredTS, Child-Pugh, C, RB, IM, OS
Sabri et al. [30]USACohort50272321 (42)55.052.01 yearGV bleeding (isolated GV)CoveredTS, C, OS, RB, H
Lee et al. [24]KoreaCohort135498658.558.52 yearsGV bleedingRB, OS, C,
Sauk et al. [26]USACohort52272524 (46)58.059.0GV bleeding (isolated GV)C, RB,
Lee et al. [25]KoreaCohort1003268GV bleedingTS, RB, C, OS
Ninoi et al. [31]JapanCohort76275834 (58)58.760.35 yearsGV bleedingBareTS, OS, Child-Pugh, C, RB, H
Choi et al. [33]KoreaRCT14774 (29)54.060.31 yearGV bleedingBare/coveredOS, Child-Pugh, C, RB, IM

OS: overall survival; PSG: portosystemic gradient; GV: gastric variceal; IM: immediate haemostasis; RB: rebleeding; C: complications; TS: technical success; H:haemostasis. Ninoi et al. compared TIPS with transcatheter sclerotherapy (including BRTO). We extracted relevant data about BRTO from the article. The mean duration of follow-up was 19.5 months for patients in the TIPS group (range, 1–52 mo.) and 18.2 months for patients in the BRTO group (range, 1–49 mo.). The follow-up period after the procedures was 41.2 ± 32.4 months in the TIPS group and 26.9 ± 16.5 months in the transcatheter sclerotherapy group (including BRTO). Patients were followed up for 6 to 21 (mean, 14.4) months. _Not mentioned.