Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease
Table 2
Biochemical analyses.
Parameters
Normal
HFD-fed mice
Veh
O60
PCM50
PCM100
Serum
ROS (flu/min/mL)
5094 ± 219
6631 ± 941
5425 ± 294
5543 ± 180
5274 ± 547
TG (mg/dL)
187.3 ± 6.6
220.7 ± 5.7
198.9 ± 1.6
195.0 ± 2.3
189.5 ± 1.0
TC (mg/dL)
130.9 ± 1.4
196.6 ± 4.0
161.9 ± 4.6
184.5 ± 4.7
160.3 ± 12.2
HDL (mg/dL)
82.4 ± 0.5
96.1 ± 0.7
97.3 ± 7.1
103.8 ± 0.6
98.2 ± 2.7
LDL (mg/dL)
15.9 ± 1.1
45.1 ± 1.7
33.2 ± 2.1
39.3 ± 2.7
39.8 ± 0.9
VLDL (mg/dL)
39.6 ± 1.2
44.1 ± 1.1
39.8 ± 0.3
39.2 ± 0.6
37.9 ± 0.2
Liver
ROS (flu/min/mg protein)
3123 ± 127
3870 ± 218
2507 ± 93
2948 ± 63
2630 ± 187
TBARS (nmol/mg protein)
0.12 ± 0.01
0.15 ± 0.01
0.11 ± 0.0
0.11 ± 0.01
0.11 ± 0.01
TG (mg/mg protein)
2.87 ± 0.09
3.33 ± 0.3
2.12 ± 0.06
2.94 ± 0.12
2.23 ± 0.05
TC (mg/mg protein)
2.42 ± 0.08
2.81 ± 0.25
1.76 ± 0.04
2.48 ± 0.1
2.07 ± 0.16
Veh, HFD control mice; O60, orlistat 60 mg/kg-treated and obese mice; PCM50, PCM 50 mg/kg-treated and obese mice; PCM100, PCM 100 mg/kg-treated and obese mice. Data are the mean ± SEM, n = 7. Significance: < 0.05, < 0.01, and < 0.001 versus HFD control mice.
