Treatment Effect of a Vascular-Disrupting Agent Dynamically Monitored by DWI: An Animal Experimental Study

Figure 7

CD34 staining (×400) of the tumor at baseline, 4 h, 1, 4, 7, and 14 days after treatment in the two groups. From 4 hours and day 1 to day 4, a decrease in the tumor blood vessels and an increase on day 7 and 14 were observed in the M410 treated group (the first line). However, there was no such change in the control group; tumor blood vessels were abundant at all time points in the saline-treated group (the second line).