Effect of Hyperthermic Intraperitoneal Perfusion Chemotherapy Combined with Radical Surgery and Capecitabine on Stage III Gallbladder Cancer
Table 1
Clinicopathological parameters of GBC patients.
Clinical features
Control group (N = 43)
HIPEC group (N = 35)
value
N
%
N
%
Age (years)
0.666
≤60
20
46.51
18
51.43
>60
23
53.49
17
48.57
Gender
0.915
Female
29
67.44
24
68.57
Male
14
32.56
11
31.43
Stones
0.222
Negative
15
34.88
17
48.57
Positive
28
65.12
18
51.43
Tumor location
0.967
Bottom and body of gallbladder
26
60.47
21
60.00
Gallbladder neck and cystic duct
17
39.53
14
40.00
CEA
0.177
Normal
28
65.12
24
68.57
High
15
33.88
11
31.43
CA19-9
0.156
Normal
24
55.81
25
71.43
High
19
44.19
10
28.57
CA125
0.872
Normal
29
67.44
23
65.71
High
14
32.36
12
34.29
CA242
0.995
Normal
27
62.79
22
62.86
High
16
37.21
13
37.14
Lymph node metastasis
0.906
Negative
24
55.81
20
57.14
Positive
19
44.19
15
42.86
Microvascular infiltration
0.369
Negative
32
74.42
29
82.86
Positive
11
25.58
6
17.14
Nerve invasion
0.956
Negative
28
65.12
23
65.71
Positive
15
34.88
12
34.29
Body surface area (m2)
1.54 ± 0.49
1.58 ± 0.35
0.492
Tumor size (cm)
3.6 ± 1.6
4.1 ± 1.4
0.109
Operation time (minutes)
335 ± 103
350 ± 65
0.586
Hospital stay (days)
20.0 ± 5.8
23.0 ± 6.9
0.029∗
Note: χ2 test was used to compare the distribution of clinical features between control group patients and HIPEC group patients. CA19-9 normal reference range: 0–35 U/mL. CA242 normal reference range: 0–20 U/mL. CEA normal reference range: 0–5 ng/mL. CA125 normal reference range: 0–35 U/mL. value < 0.05 was considered significant.
