Research Article
Systemic Inflammatory Response Syndrome in Patients Hospitalized for Acute Decompensation of Cirrhosis
Table 4
Comparison of demographic, clinical, and laboratory data according to 90-day survival among patients with SIRS (n = 232).
| | | Survivors (n = 150) | Nonsurvivors (n = 82) | HR (95% CI) | |
| | Age (years), mean ± SD | 54.0 ± 13.9 | 55.2 ± 11.4 | 1.004 (0.988–1.021) | 0.608 | | Male gender (%) | 64.7 | 65.9 | 1.048 (0.664–1.654) | 0.842 | | Diabetes (%) | 36.9 | 38.3 | 1.061 (0.630–1.785) | 0.825 | | Beta-blockers (%) | 38.0 | 35.9 | 0.914 (0.576–1.452) | 0.704 |
| | Complication at admission (%) | | | | | | Ascites | 52.0 | 80.5 | 2.935 (1.699–5.073) | <0.001 | | Hepatic encephalopathy | 36.7 | 28.0 | 1.576 (1.013–2.451) | 0.043 | | Gastrointestinal bleeding | 48.0 | 59.8 | 0.742 (0.458–1.202) | 0.225 | | Bacterial infection, (%) | 52.0 | 81.7 | 3.328 (1.900–5.831) | <0.001 |
| | Laboratory data | | | | | | Sodium (mEq/L), mean ± SD | 135.1 ± 5.8 | 132.2 ± 6.5 | 0.945 (0.916–0.976) | 0.001 | | Albumin (g/dL), mean ± SD | 2.5 ± 0.7 | 2.1 ± 0.5 | 0.454 (0.322–0.639) | <0.001 | | INR, median | 1.4 | 1.6 | 1.583 (1.294–1.937) | <0.001 | | Total bilirubin (mg/dL), median | 2.0 | 3.6 | 1.069 (1.046–1.092) | <0.001 | | Creatinine (mg/dL), median | 1.0 | 1.7 | 1.265 (1.161–1.379) | <0.001 | | Leukocyte count (x109), median | 6.07 | 9.03 | 1.049 (1.024–1.075) | <0.001 | | CRP (mg/L), median | 8.5 | 14.9 | 1.005 (1.002–1.008) | 0.002 |
| | MELD score, mean ± SD | 15.8 ± 6.0 | 23.3 ± 8.4 | 1.094 (1.070–1.120) | <0.001 | | ACLF (%) | 19.6 | 59.8 | 4.176 (2.679–6.512) | <0.001 | | Child-pugh C (%) | 37.5 | 74.4 | 3.604 (2.192–5.924) | <0.001 | | MAP (mmHg), mean ± SD | 85.7 ± 14.5 | 84.6 ± 16.8 | 0.995 (0.981–1.010) | 0.526 |
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SIRS = systemic inflammatory response syndrome; HR = hazard ratio; SD = standard deviation; INR = international normalised ratio; CRP = C-reactive protein; MELD = Model for End-Stage Liver Disease; ACFL = acute-on-chronic liver failure; MAP = mean arterial pressure.
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