Research Article

Spleen Stiffness for Predicting Varices Needing Treatment: Comparison between Two Different Elastography Techniques (Point vs. 2D-SWE)

Table 1

Main characteristics of subjects enrolled in the study.

ParameterAll subjects with reliable SSM (n = 98)No VNT n = 58 (59.2%)VNT n = 40 (40.8%) value

Age59 ± 9.4759.9 ± 8.7257.2 ± 10.7

Gender
 Male44% (43/98)32.8% (19/58)60% (24/40)
 Female56% (55/98)67.2% (39/58)40% (16/40)

Etiology
 HCV71.5% (70/98)77.6% (45/58)62.5% (25/40)
 HBV4% (4/98)5.2% (3/58)2.5% (1/40)
 ALD12.3% (12/98)6.9% (4/58)20% (8/40)
 NAFLD8.2% (8/98)5.2% (3/58)12.5% (5/40)
 PBC4% (4/98)5.1% (3/58)2.5% (1/40)

Platelet count (x109/L)121.8 ± 56.9135.6 ± 55.1106.7 ± 61.6
LSM by 2D-SWE.GE12.54 ± 2.2711.5 ± 1.414.16 ± 2.34
SSM by 2D-SWE.GE<14.36 ± 3.3912.71 ± 2.216.74 ± 3.4
SSM by pSWE.VTQ3.08 ± 0.542.77 ± 0.33.52 ± 0.49
Spleen size (cm)13.68 ± 1.9313.8 ± 1.6714.55 ± 1.97
EV 032/98 (32.7%)32/58 (55.2%)0/40 (0%)
EV 126/98 (26.5%)26/58 (44.8%)0/40 (0%)
EV 231/98 (31.6%)0/58 (0%)34/40 (85%)
EV 34/98 (4.1%)0/58 (0%)6/40 (15%)
EV + GV5/98 (5.1%)0/58 (0%)5/40

VNT: varices needing treatment; n: number; HCV: hepatitis C virus; HBV: hepatitis B virus; ALD: alcoholic liver disease; NAFLD: nonalcoholic fatty liver disease; PBC: primary biliary cirrhosis; LSM: liver stiffness measurements; SSM: spleen stiffness measurements; EV: esophageal varices; and GV: gastric varices.