Lactate and Bilirubin Index: A New Indicator to Predict Critically Ill Cirrhotic Patients’ Prognosis

Table 5

Diagnostic accuracy of different scoring systems in predicting 3-year mortality at the optimal cutoff point.

Prognostic models	AUROC (95% CI)	P value	Cutoff point	Sensitivity	Specificity	PPV	NPV	PLR	NLR
MELD	0.726 (0.680–0.771)	—	18	0.61	0.74	0.76	0.58	2.36	0.53
Child–Pugh	0.602 (0.552–0.652)	<0.001	10	0.76	0.41	0.64	0.55	1.28	0.59
SOFA	0.683 (0.635–0.730)	0.045	10	0.53	0.73	0.73	0.53	1.97	0.64
CLIF-SOFA	0.698 (0.651–0.744)	0.136	10	0.63	0.69	0.73	0.58	2.02	0.54
LB index	0.694 (0.648–0.741)	0.159	6.18	0.51	0.82	0.79	0.55	2.88	0.59

DeLong test was used to compare the AUC between MELD score and other clinical models. AUROC: area under the receiver operating characteristic curve; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; MELD: model for end-stage liver disease; SOFA: sequential organ failure assessment; CLIF-SOFA: chronic liver failure-sequential organ failure assessment; LB: lactate and bilirubin.