Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity

Table 2

Liver parameters at baseline and after 6 months of dietary intervention.

Variable	Anti-inflammatory diet group (n = 42)				Control diet group (n = 39)				Baseline value^b	6 months value^c
	Baseline	6 months	Change (%)	value^a	Baseline	6 months	Change (%)	value^a
AST (IU/L)	21.7 (7.9)	20.7 (6.1)	−4.8	0.516	24.0 (6.5)	23.0 (6.4)	−4.2	0.885	0.263	0.075
ALT (IU/L)	24.3 (13.5)	22.6 (11.2)	−6.8	0.914	31.9 (13.1)	29.3 (14.7)	−8.1	0.416	0.540	0.099
GGT (IU/L)	22.43 (9.9)	17.7 (6.7)	−21.3	0.011	25.4 (5.6)	21.8 (6.6)	−14.3	0.003	0.212	0.040
NAFLD-FLS	0.46 (2.2)	−0.2 (2.1)	−143.4	0.158	0.0 (0.8)	−0.1 (1.4)	−275.0	0.590	0.647	0.875
FLI	1.4 (0.6)	1.2 (0.5)	−14.3	0.040	1.6 (0.7)	1.3 (0.7)	−18.8	0.006	0.331	0.047
FIB-4	0.8 (0.2)	0.8 (0.2)	−2.5	0.452	1.2 (2.0)	0.7 (0.3)	−41.7	0.207	0.418	0.495

Data are presented as the mean (SD). AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase; NAFLD-FLS, Nonalcoholic Fatty Liver Disease Liver Fat Score; FLI, Fatty Liver Index; FIB-4, Fibrosis Index Based On Four Factors. ^aComparison within dietary groups (baseline and after 6 months). ^bBaseline differences between the AID and CD groups. ^cDifferences after 6 months between the AID and CD groups.