Research Article

Long-Term Administration of Anthraquinone Rhein on Induction of Constipation in Sprague-Dawley Rats via SCF/c-Kit Signaling Pathways

Table 2

Alteration of stool in rhein-induced constipation of rats after administration with or without PEG4,000 for 30 d (%) .

GroupsFrequency of defecation (number/rat)Fecal moisture (%)

Normal group (n = 12)32.4 ± 5.656.88 ± 3.62
Model control group (n = 12)18.2 ± 4.847.81 ± 3.98
PEG-treated group (n = 12)20.6 ± 4.2,49.20 ± 3.27,

Results are expressed as the mean ± standard deviation.  < 0.05, compared with normal group;  > 0.05, compared with model control group. PEG, polyethylene glycol.