Controlled Attenuation Parameter for Quantification of Steatosis: Which Cut-Offs to Use?

Table 2

Main advantages and weaknesses of CAP/VCTE.

Advantages	Weaknesses
(i) Reproducible method	(i) Expensive equipment
(ii) Well accepted by the patients and thus repeatable assessment possible for follow-up	(ii) Not feasible in patients with ascites
(iii) Good results for noninvasive steatosis assessment in patients with CLD, including NASH	(iii) Increased number of unreliable measurements in patients with high BMI, especially with M probe
(iv) CAP could be used as a screening tool in patients at risk for NAFLD/NASH	(iv) CAP not very accurate to differentiate S ≥ 2 from S3
(v) Real-time assessment not only of steatosis but also of fibrosis severity	(v) TE not very accurate to differentiate patients without fibrosis and those with mild fibrosis and patients with moderate vs. mild fibrosis
(vi) Reliable tool for noninvasive assessment of fibrosis, recognized by international guidelines	—
(vii) Results and technical parameters IQR/M available in real time, automatically calculated by the device’s software	—

CAP: controlled attenuation parameter; VCTE: vibration-controlled transient elastography.