Research Article

Safety and Efficacy of the Noncessation Method of Antithrombotic Agents after Emergency Endoscopic Hemostasis in Patients with Nonvariceal Upper Gastrointestinal Bleeding: A Multicenter Pilot Study

Table 4

Characteristics of patients before and after propensity score matching in groups A and B.

Before propensity score matching
Group AGroup B valueStandardized differences

Number of patients (N)43154
Age (years)77.8 ± 9.172.8 ± 12.40.0040.47
Gender, male28 (65.1%)108 (70.1%)0.580.11
Helicobacter pylori infection20 (46.5%)107 (69.5%)0.0070.48
Number of antithrombotics, multiple11 (25.6%)38 (24.7%)1.000.02
Antiplatelet agents30 (69.8%)133 (86.4%)0.020.41
Anticoagulant agents17 (39.5%)33 (21.4%)0.030.40
Location of ulcer, gastric34 (79.1%)108 (84.4%)1.000.14
Number of ulcers, single28 (65.1%)80 (62.5%)0.860.05
Size of ulcer, >11 mm21 (48.8%)83 (64.8%)0.070.33

After propensity score matching
Group AGroup B valueStandardized differences

Number of patients (N)4040
Age (years)77.1 ± 8.978.2 ± 8.00.550.13
Gender, male26 (65.0%)24 (60.0%)0.820.10
Helicobacter pylori infection19 (47, 5%)20 (50.0%)1.000.05
Number of antithrombotics, multiple11 (27.5%)12 (30.0%)1.000.05
Antiplatelet agents30 (75.0%)31 (77.5%)1.000.06
Anticoagulant agents14 (35.0%)12 (30.0%)0.810.11
Location of ulcer, gastric33 (82.5%)36 (90.0%)0.520.22
Number of ulcers, single26 (65.0%)26 (65.0%)1.000.00
Size of ulcer, >11 mm21 (52.5%)22 (55.0%)1.000.05

Group A: patients taking antithrombotic agents who underwent emergency endoscopic hemostasis for nonvariceal upper gastrointestinal bleeding and resumed antithrombotic medication without a cessation period; group B: patients taking antithrombotic agents who underwent emergency endoscopic hemostasis for nonvariceal upper gastrointestinal bleeding for whom antithrombotic medication was transiently discontinued.