Ursodeoxycholic Acid at 18–22 mg/kg/d Showed a Promising Capacity for Treating Refractory Primary Biliary Cholangitis

Table 5

Fibrosis risk score testing at the 6th and 12th month.

	13–15 mg/kg/d	18–22 mg/kg/d	value
6 month
APRI	1.016 (0.530, 2.012)	0.615 (0.473, 1.135)	0.041
FIB-4	2.501 (1.550, 4.814)	1.729 (1.193, 2.549)	0.018
12 month
APRI	1.165 (0.641, 2.038)	0.731 (0.467, 1.114)	0.008
FIB-4	2.874 (1.794, 4.993)	2.036 (1.343, 2.691)	0.013

Note. APRI, aspartate aminotransferase/platelet ratio index; FIB-4, fibrosis index based on the four factors.