Ursodeoxycholic Acid at 18–22 mg/kg/d Showed a Promising Capacity for Treating Refractory Primary Biliary Cholangitis

Table 6

Percentage of biochemical relative changes from baseline at 6 months.

%Change from baseline	13–15 mg/kg/d	18–22 mg/kg/d	value
	(n = 36)	(n = 37)
TB, μ mol/L	6.79 (−12.31, 23.09)	9.69 (−9.91, 26.70)	0.544
ALP, IU/L	9.60 (−4.03, 28.13)	16.09 (4.02, 28.12)	0.238
GGT, IU/L	31.57 (7.83, 42.76)	−29.18 (19.22, 40.03)	0.974
AST, IU/L	10.56 (−4.80, 28.25)	15.15 (5.00, 32.67)	0.544
ALT, IU/L	10.71 (−4.27, 34.31)	21.28 (0.55, 39.00)	0.522
ALB, g/L	−2.21 (−8.37, 2.97)	1.76 (−1.89, 6.17)	0.013
GLB, g/L	2.18 (6.19, 6.70)	2.23 (−2.51, 9.94)	0.460
PLT, 10^9/L	−9.49 (21.55, 1.59)	1.72 (−12.71, 22.83)	0.034
IGM, mg/L	8.36 (−5.45, 19.09)	6.67 (0.72, 15.04)	0.501

Note. TB, total bilirubin; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALB, albumin; GLB, globulin; GGT, γ-glutamyltransferase; IGM, immunoglobulin M; PLT, platelet count.