Research Article
Adenocarcinoma with Mixed Subtypes in the Early and Advanced Gastric Cancer
Table 5
Results of competing risks regression with inclusion of possible risk factors in patients with early gastric cancer.
| Variable | Subdistribution hazard ratio | value |
| Sex | Female | 1.218 (1.014 − 1.463) | 0.035 | Male | Age | <65 | 1 (reference) | | ≥65 | 1.431 (1.177 − 1.739) | <0.001 | Race | White | 1 (reference) | | Black | 0.985 (0.750 − 1.294) | 0.910 | Others | 0.774 (0.614 − 0.975) | 0.029 | Tumor size | <3 cm | 1 (Reference) | | 3–6 cm | 1.518 (1.213 − 1.900) | <0.001 | ≥6 cm | 1.692 (1.342 − 2.134) | <0.001 | Primary site | Antrum | 1 (reference) | | Pylorus | 1.027 (0.761 − 1.384) | 0.860 | Body | 1.539 (1.169 − 2.026) | 0.002 | Cardia | 2.008 (1.360 − 2.964) | <0.001 | Fundus | 1.165 (0.809 − 1.680) | 0.410 | Lesser curve | 1.173 (0.799 − 1.722) | 0.410 | Greater curve | 1.306 (0.962 − 1.771) | 0.087 | Overlapping/not otherwise specified | 1.086 (0.506 − 2.331) | 0.830 | N stage | N0 | 1 (reference) | | N1 | 1.033 (0.803 − 1.330) | 0.800 | N2 | 1.234 (0.672 − 2.266) | 0.500 | N3 | 1.882 (1.073 − 3.301) | 0.027 | M stage | M0 | 1 (reference) | | M1 | 3.184 (2.479 − 4.090) | <0.001 | Surgery | None | 1 (reference) | | Local tumor destruction | 0.112 (0.059 − 0.213) | <0.001 | Partial gastrectomy | 0.156 (0.120 − 0.205) | <0.001 | Total gastrectomy | 0.174 (0.123 − 0.245) | <0.001 | Pathology | AMa | 1 (reference) | | CAb | 1.035 (0.666 − 1.608) | 0.520 | MACc | 1.794 (0.697 − 2.045) | 0.880 | SRCCd | 1.289 (0.840 − 1.976) | 0.240 |
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aAdenocarcinoma with mixed subtypes; bclassical adenocarcinoma; cmucinous adenocarcinoma; dsignet-ring cell carcinoma.
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