Adenocarcinoma with Mixed Subtypes in the Early and Advanced Gastric Cancer

Table 5

Results of competing risks regression with inclusion of possible risk factors in patients with early gastric cancer.

Variable	Subdistribution hazard ratio	value
Sex
Female	1.218 (1.014 − 1.463)	0.035
Male
Age
<65	1 (reference)
≥65	1.431 (1.177 − 1.739)	<0.001
Race
White	1 (reference)
Black	0.985 (0.750 − 1.294)	0.910
Others	0.774 (0.614 − 0.975)	0.029
Tumor size
<3 cm	1 (Reference)
3–6 cm	1.518 (1.213 − 1.900)	<0.001
≥6 cm	1.692 (1.342 − 2.134)	<0.001
Primary site
Antrum	1 (reference)
Pylorus	1.027 (0.761 − 1.384)	0.860
Body	1.539 (1.169 − 2.026)	0.002
Cardia	2.008 (1.360 − 2.964)	<0.001
Fundus	1.165 (0.809 − 1.680)	0.410
Lesser curve	1.173 (0.799 − 1.722)	0.410
Greater curve	1.306 (0.962 − 1.771)	0.087
Overlapping/not otherwise specified	1.086 (0.506 − 2.331)	0.830
N stage
N0	1 (reference)
N1	1.033 (0.803 − 1.330)	0.800
N2	1.234 (0.672 − 2.266)	0.500
N3	1.882 (1.073 − 3.301)	0.027
M stage
M0	1 (reference)
M1	3.184 (2.479 − 4.090)	<0.001
Surgery
None	1 (reference)
Local tumor destruction	0.112 (0.059 − 0.213)	<0.001
Partial gastrectomy	0.156 (0.120 − 0.205)	<0.001
Total gastrectomy	0.174 (0.123 − 0.245)	<0.001
Pathology
AM^a	1 (reference)
CA^b	1.035 (0.666 − 1.608)	0.520
MAC^c	1.794 (0.697 − 2.045)	0.880
SRCC^d	1.289 (0.840 − 1.976)	0.240

^aAdenocarcinoma with mixed subtypes; ^bclassical adenocarcinoma; ^cmucinous adenocarcinoma; ^dsignet-ring cell carcinoma.