|
| SNP | Variant genotypes | Variable genotype frequency (%) in premalignant gastric lesions vs. control | Premalignant gastric lesions | References |
|
| TNF-α-308 | GA
AA | 15 (29.4)/22 (20.4)
0 (0)/3 (2.8) | Chronic atrophic gastritis susceptibility | [88] |
| IL-1B-511 | CT
TT | 18 (35.3)/53 (49.1)
3 (5.9)/13 (12.0) | Chronic atrophic gastritis susceptibility |
| IL-1RN | L/2
2/2 | 15 (29.4)/32 (29.6)
2 (3.9)/13 (12.0) | Chronic atrophic gastritis susceptibility |
|
| TNF-α-308 | GA
AA | 125 (23.4)/129 (24.2)
13 (2.4)/8 (1.5) | Chronic atrophic gastritis susceptibility | [89] |
| IL-10 T-819C | TC
CC | 200 (37.5)/199 (37.3)
44 (8.2)/28 (5.2) | Chronic atrophic gastritis susceptibility |
| IL-10 A-1082G | AG
GG | 246 (46.1)/262 (49.1)
109 (20.4)/116 (21.7) | Chronic atrophic gastritis susceptibility |
|
| IL-10-1082 | AA
GA | 35 (60.3)/81 (49.1)
17 (29.3)/56 (33.9) | Atrophic gastritis risk | [90] |
AA
GA | 17 (54.8)/99 (51.6)
10 (32.3)/63 (32.8) | Corpus atrophic gastritis risk |
AA
GA | 12 (52.2)/104 (46/6)
10 (43.5)/63 (28.3) | Intestinal metaplasia risk |
| IL-10-592 | AA
CA | 8 (13.8)/12 (7.3)
19 (32.8)/58 (35.1) | Atrophic gastritis risk |
AA
CA | 4 (12.9)/16 (8.3)
10 (32.3)/67 (34.9) | Corpus atrophic gastritis risk |
AA
CA | 4 (17.4)/16 (7.2)
8 (34.8)/69 (30.9) | Intestinal metaplasia risk |
|
| IL10–1082 | AG
AA | 102 (35.3)/406 (37.5)
142 (49.1)/508 (46.9) | Atrophic gastritis risk | [91] |
AG
AA | 201 (37.0)/406 (37.5)
274 (50.5)/508 (46.9) | Intestinal metaplasia risk |
AGa
AAa | 51 (43.2)/406 (37.5)
60 (50.8)/508 (46.9) | Dysplasia risk |
|
| IL-10-1082 | AG
GG | 15 (12.9)/18 (7.8)
0 (0)/1 (0.4) | Atrophic gastritis susceptibility | [92] |
| IL-10-819 | CT
CC | 47 (40.5)/104 (44.8)
28 (24.1)/36 (15.5) | Atrophic gastritis susceptibility |
| IL-10-592 | AC
CC | 46 (39.7)/96 (41.4)
31 (26.7)/52 (22.4) | Atrophic gastritis susceptibility |
|
| IL-10-819 | CT
TT | 55 (41.9)/21 (55.3)
10 (7.6)/6 (15.8) | Gastritis | [93] |
| IL-10-819 | CT
TT | 21 (42.9)/21 (55.3)
5 (10.2)/6 (15.8) |
|
