Negative Video Capsule Endoscopy Had a High Negative Predictive Value for Small Bowel Lesions, but Diagnostic Capability May Be Lower in Young Patients with Overt Bleeding
Table 3
Univariate and multivariate analyses for factors significantly associated with rebleeding after negative video capsule endoscopy.
Factors
Univariate HR (95% CI)
Multivariate HR (95% CI)
Age
1.004 (0.982–1.027)
0.707
1.007 (0.985–1.029)
—
Male gender
2.151 (0.985–4.698)
0.054
1.501 (0.660–3.414)
—
Diabetes
1.025 (0.456–2.305)
0.952
—
—
Atherosclerosis∗
0.936 (0.429–2.045)
0.869
—
—
Chronic kidney disease
0.559 (0.195–1.604)
0.280
—
—
Colonic diverticulosis
1.318 (0.562–3.088)
0.526
—
—
NSAIDs use
7.254 (2.495–21.088)
0.0003
6.430 (2.111–19.584)
0.0011
Antiplatelet use
0.721 (0.319–1.627)
0.430
—
—
Anticoagulant use
1.375 (0.562–3.366)
0.486
—
—
Overt bleeding
2.350 (1.045–5.281)
0.039
2.275 (0.998–5.184)
0.0504
Duration of presentation
1.000 (0.998–1.001)
0.790
—
—
Abdominal pain
0.532 (0.072–3.908)
0.535
—
—
Weight loss
0.847 (0.115–6.220)
0.871
—
—
Hemoglobin level
0.957 (0.823–1.113)
0.567
—
—
Albumin level
0.831 (0.416–1.658)
0.599
—
—
∗Atherosclerosis included any coronary artery, cerebrovascular, or peripheral vascular disease. HR: hazard ratio; CI: confidence interval; NSAIDs: nonsteroidal anti-inflammatory drugs.