Low Serum miR-607 Level as a Potential Diagnostic and Prognostic Biomarker in Patients of Pancreatic Ductal Adenocarcinoma: A Preliminary Study

Table 2

Univariate Cox regression analysis of different prognostic factors for OS in PDAC patients.

Features	Univariate analysis
	RR	95% CI	value
Age (≥60 years vs. < 60 years)	1.132	0.706–1.894	0.442
Gender (male vs. Female)	0.763	0.488–1.268	0.715
Tumor size (≥3 cm vs. < 3 cm)	1.585	0.896–2.727	0.315
Differentiation (poor vs. Well - moderate)	1.749	0.950–3.419	0.062
Clinical stage (III-IV vs. I-II)	3.758	1.566–7.383	<0.001
T Stage (T3-T4 vs. T1-T2)	1.683	0.775–2.849	0.174
Lymphatic metastasis (positive vs. Negative)	2.565	1.368–4.893	0.005
Perineural invasion (positive vs. Negative)	3.692	1.702–6.659	<0.001
Liver metastasis (positive vs. Negative)	2.802	1.251–4.943	0.001
CEA level (≥5 ng/mL vs. < 5 ng/mL)	0.581	0.362–1.409	0.694
CA19-9 level (≥35 U/mL vs. < 35 U/mL)	1.601	0.718–2.972	0.072
miR-607 level (high vs. low)	0.365	0.169–0.790	0.011

OS: overall survival, RR: risk ratio, CI: confidence interval.