Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B

Figure 2

sGDNF levels according to the histological grade and fibrosis stage in 344 patients. Liver histopathology of patients with G0, G1, G2, G3, and G4 according to the Scheuer scoring system. G1, portal inflammation; G2, mild piecemeal necrosis; G3, moderate piecemeal necrosis; G4, severe piecemeal necrosis and bridging necrosis. METAVIR scoring system. F0, no fibrosis; F1, portal fibrosis without septa; F2, septal fibrosis (portal-portal); F3, septal fibrosis (portal-central); F4, cirrhosis.