Biologic Agents in Crohn’s Patients Reduce CD4⁺ T Cells Activation and Are Inversely Related to Treg Cells

Figure 4

Presence of Treg suppressor on the intestine. (a) Six immunostaining with the specific antibodies. From right to left, we have the merged images. The top right is an example of lesion tissue and bottom-right healthy margins. The six quadrants from the left show an example of a single stain. (b) Counting of suppressor Treg cells in the intestine. Each dot represents the median of the count. Statistical analysis was performed using the Mann–Whitney test.

(a)

(b)