Recipient Age Predicts 20-Year Survival in Pediatric Liver Transplant

Table 1

Demographics and clinical characteristics of allografts and recipients of 1-year survivors.

	Survival <20 years	Survival >20 years	-value
Total recipients	3144	1168	NA
Recipient demographics and characteristics
Recipient age	5.74 ± 5.99	4.01 ± 5.20	<0.001
Weight (kg)	23.40 ± 21.61	17.54 ± 18.21	<0.001
Diagnosis: biliary atresia	432 (13.74%)	211 (18.11%)	<0.001
Diagnosis: metabolic dysfunction	126 (4.01%)	75 (6.42%)	<0.001
Albumin (mg/dL)	3.17 ± 0.70	3.21 ± 0.69	0.072
Creatinine	0.60 ± 0.82	0.50 ± 0.80	<0.001
Hemodialysis at transplant	34 (1.08%)	13 (1.11%)	0.929
No previous transplants	2430 (77.29%)	986 (84.42%)	<0.001
1 previous transplant	362 (11.51%)	97 (8.30%)	0.002
2 previous transplants	51 (1.62%)	7 (0.60%)	0.010
Intensive care at transplant	1017 (32.35%)	305 (26.11%)	<0.001
Life support at transplant	616 (19.59%)	174 (14.90%)	<0.001
Recipient total bilirubin	12.95 ± 11.93	12.11 ± 11.83	0.041
Ascites	692 (22.01%)	269 (23.03%)	0.474
BMI	18.88 ± 9.91	18.04 ± 9.27	0.022
Encephalopathy at transplant	200 (6.36%)	64 (5.50%)	0.283
African-American recipient	585 (18.60%)	157 (13.44%)	<0.001
Ventilation at transplant	582 (18.51%)	161 (13.78%)	<0.001
Private insurance	688 (21.88%)	290 (23.03%)	0.040
Previous abdominal surgery	666 (21.18%)	293 (25.10%)	0.006
Time listed before transplant (Years)	0.32 ± 0.54	0.36 ± 0.63	0.051
Donor and allograft demographics and characteristics
Donor age	14.15 ± 15.00	10.14 ± 12.11	<0.001
African-American donor	430 (13.68%)	152 (13.01%)	0.571
Cause of death: cerebrovascular accident	506 (16.09%)	142 (12.16%)	<0.001
Cause of death: deceased cardiac donor	2 (0.06%)	2 (0.17%)	0.022
Live donor transplant	247 (7.86%)	76 (6.51%)	0.135
Split transplant	386 (12.28%)	156 (13.36%)	0.342
Cold ischemia time (hours)	10.57 ± 5.90	10.73 ± 6.31	0.437
Donor total bilirubin	0.99 ± 2.63	0.99 ± 2.62	0.71
Donor: diabetes mellitus	17 (0.54%)	4 (0.34%)	0.406