Research Article

Insulin Resistance Markers to Detect Nonalcoholic Fatty Liver Disease in a Male Hispanic Population

Table 1

Baseline characteristics according to the presence of nonalcoholic fatty liver disease (NAFLD).

Subjects with NAFLD (n = 70)Subjects without NAFLD (n = 193) value

Age (years)39.31 (±5.31)38.35 (±5.97)0.13
BMI (kg/m2)26.88 (±2.56)23.92 (±2.52)<0.001
Waist circumference (cm)94.4 (±5.8)86.8 (±6.7)<0.001
Hip circumference (cm)97.9 (±9.3)92.5 (±5.1)<0.001
Waist-to-hip ratio0.97 (±0.06)0.95 (±0.05)<0.001
Subcutaneous fat (mm)19.4 (±6.7)15.2 (±4.7)<0.001
Visceral fat (mm)40.8 (±12.7)27.4 (±12.2)<0.001
Systolic blood pressure (mmHg)116.19 (±14.43)113.23(13.97)0.142
Diastolic blood pressure (mmHg)74.01 (±9.5)71.2 (±10.0)0.042
Fasting glycemia (mg/dl)92.5 (±8.01)91.03 (±8.35)0.182
Post 75 g OGTT glycemia (mg/dl)91.23 (±27.54)81.16 (±20.4)0.006
TG (mg/dl)238 (±136.6)152 (±78.76)<0.001
HDL (mg/dl)38.73 (±7.46)47.57 (±11.5)<0.001
Insulin (µIU/ml)11.01 (±5.13)6.64 (±3.64)<0.001
Uric acid (mg/dl)7.01 (1.2)6.38 (1.29)<0.001
GGT (IU/l)67.1 (81.57)36.62 (32.51)0.003
HOMA-IR2.55 (±1.36)1.51 (±0.91)<0.001
TyG index9.17 (±0.53)8.72 (±0.51)<0.001
TG/HDL ratio6.6 (±4.54)3.52 (±2.32)<0.001

BMI, body mass index; OGTT, oral glucose tolerance test; TG, triglycerides; HDL, high-density lipoprotein; GGT, gamma-glutamyl transferase; HOMA-IR, the homeostasis model assessment index; TyG, triglycerides/glucose; TG/HDL, triglycerides/high-density lipoprotein.