Risk Factors and Timing of Additional Surgery after Noncurative ESD for Early Gastric Cancer

Table 5

Comparison of safety and radical resection between different surgery timing for early gastric cancer.

	Early surgery after ESD (n = 19)	Delayed surgery after ESD (n = 11)	Direct surgery (n = 59)	P1 (early vs. delayed)	P2 (early vs. direct)	P3 (delayed vs. direct)
Age (year)	61.4 ± 10.3	63.5 ± 8.9	62.7 ± 11.4	0.532	0.312	0.571
Gender (male)	17	8	33	0.093	0.012	0.037
BMI (kg/m^2)	22.1 ± 4.2	24.5 ± 3.9	23.6 ± 4.7	0.211	0.421	0.542
Extent of gastric resection
Distal gastrectomy	13	8	42	0.533	0.242	0.471
Proximal gastrectomy	2	1	6
Total gastrectomy	4	2	11
Surgery approach
Laparoscopic	12	8	38	0.231	0.123	0.701
Open	7	3	21
Operation time (min)	289 ± 74	230 ± 66	245 ± 102	0.046	0.072	0.144
Intraoperative blood loss (ml)	421 ± 218	252 ± 102	321 ± 138	0.012	0.025	0.059
No. of LN dissection	22 ± 7	19 ± 8	23 ± 7	0.634	0.453	0.323
LN metastasis rate	15.8% (3/19)	18.2% (2/11)	13.6% (8/59)	0.324	0.279	0.145
Postoperative flatus and defecation time (d)	6.1 ± 2.8	4.8 ± 2.2	4.9 ± 3.1	0.139	0.051	0.231
Postoperative oral feeding time (d)	5.3 ± 3.8	4.7 ± 3.5	4.7 ± 2.9	0.711	0.213	0.572
Postoperative hospital stay (d)	12.3 ± 5.8	10.5 ± 4.1	9.8 ± 2.9	0.062	0.031	0.342
Postoperative complications (n)	4	3	12	0.312	0.192	0.211