Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients

Table 4

Characteristics of the deceased patients.

	Patient 1	Patient 2	Patient 3	Patient 4
Age	59	49	68	72
Sex	Male	Female	Female	Female
AIH presentation	Fulminant	Fulminant	Fulminant	Fulminant
Chronic hepatitis	Yes	No	No	Yes
Necrosis	No	No	Severe	No
Fibrosis	F4	F4	F1	F1
Treatment with steroids	Yes	No	No	Yes
Liver transplantation	Yes	Yes	Yes	No
Total bilirubin—(mg/dL)	30.3	28.8	7.2	17.5
AST/ALT—(U/L)	378/433	863/602	9547/4276	1847/1012
Immunoglobulin G—(mg/dL)	1900	1070	1530	2450
Prothrombin—(%)	26	40	48	44
MELD	30	25	19	23
ANA	1/640	1/80	1/80	1/640
SMA	1/640	1/320	(—)	1/320
Cause of death	Septic shock	Septic shock	Septic shock	Septic shock

AST: aspartate aminotransferase; ALT: alanine aminotransferase; ANA: antinuclear antibody; SMA: smooth muscle antibody; MELD: model of end-stage liver disease.