Review Article

Kiwifruit and Kiwifruit Extracts for Treatment of Constipation: A Systematic Review and Meta-Analysis

Table 4

Summary of findings table: kiwi compared to psyllium for constipation.

Certainty assessmentNo. of patientsEffectCertaintyImportance
No of studiesStudy designRisk of biasInconsistencyIndirectnessImprecisionOther considerationsKiwiPsylliumRelative (95% CI)Absolute (95% CI)

Weekly frequency of spontaneous bowel movements (higher number indicates an increase frequency) (follow-up: range 14 days to 30 days; assessed with: weekly mean number of SBM)
3Randomized trialsSerious aNot serious bNot seriousNot seriousNone178171MD 1.01 weekly spontaneous bowel movements higher (0.02 lower to 2 higher)⊕⊕⊕◯ MODERATECRITICAL

Bristol stool scale (higher number indicates softer stool) (follow-up: range 14 days to 28 days; assessed with BSS 1–7 scale)
2Randomized trialsSerious aNot seriousNot seriousSerious cNone6154MD 0.63 BSS higher (0.01 higher to 1.3 higher)⊕⊕◯◯ LOWIMPORTANT

Abdominal pain (follow-up: range 14 days to 28 days; assessed with: Abdominal pain scale)
2Randomized trialsSerious aNot seriousNot seriousSerious c,dNone6154SMD 0.16 SD lower (0.6 lower to 0.2 higher)⊕⊕◯◯ LOWIMPORTANT

Straining frequency (lower number indicates improvement) (follow-up: range 14 days to 28 days; assessed with: weekly frequency of straining)
2Randomized trialsSerious aNot seriousNot seriousSeriousNone6154MD 0.2 weekly frequency lower (1.3 lower to 0.9 higher)⊕⊕◯◯ LOWIMPORTANT

CI: confidence interval; MD: mean difference; SMD: standardized mean difference. (a) Chey, 2021, had major issues with randomization and allocation concealment. Included data from abstract published by Barbara, no access to the full article. (b) We did not rate down for inconsistency as some of the elements have been incorporated in rating down of risk of bias and imprecision. (c) Small sample size. (d) Confidence interval is wide, crosses the null, and includes harm.