The Prognostic Value of Serum HBV-RNA during Hepatitis B Virus Infection is Related to Acute-on-Chronic Liver Failure

Table 1

The baseline characteristics of the population.

Characteristics	HBV-ACLF n = 82	CHB n = 33	value
Demography
Male, n (%)	65 (79.27)	24 (72.73)	0.57
Age, years	47.18 ± 11.44	43.29 ± 10.28	0.23
Cirrhosis, n (%)	29 (35.4)	NA
Treatment
ETV, n (%)	56	NA
TDF, n (%)	24	NA
TAF, n (%)	1
MELD score	23.19 ± 4.66	NA
Laboratory results
HBeAg positive, n (%)	30 (36.59)	15 (45.45)	0.18
qHBsAg, log10 IU/mL	2.62 ± 1.37	2.98 ± 1.75	0.26
qHBV DNA, log10 IU/mL	5.51 ± 2.04	5.98 ± 1.57	0.71
qHBV RNA, log10 copies/mL	4.15 ± 2.13	5.37 ± 2.02	0.006
INR	2.92 ± 1.41	1.2 ± 0.3	0.001
Alb, g/L	30.91 ± 4.06	41.28 ± 3.78	0.014
TBil, mg/dL	17.01 (4.30, 29.51)	0.84 (0.58, 2.74)	0.001
ALT, IU/L	411.00 (34.28, 2068.17)	48.11 (11.25, 218.69)	0.001
AST, IU/L	352.00 (29.30, 1744.29)	35.26 (7.18, 198.21)	0.001
Scr, mg/dL/L	0.64 (0.47, 1.43)	1.24 (0.97, 1.87)	0.001
WBC, 10^^9/L	6.64 (4.18, 9.87)	5.84 (3.29, 8.86)	0.28
Ne, 10^^9/L	4.82 (3.39, 7.07)	5.14 (4.18, 8.29)	0.39
Plt, 10^^9/L	89.78 (64, 134)	188 (108, 297)	0.001
Lym, 10^^9/L	1.78 (0.65, 1.39)	1.56 (0.38, 1.76)	0.49