The Prognostic Value of Serum HBV-RNA during Hepatitis B Virus Infection is Related to Acute-on-Chronic Liver Failure

Table 2

The comparison of the surviving and nonsurviving patients with HBV-ACLF.

Characteristics	Surviving n = 46	Nonsurviving n = 36	value
Demography
Male, n (%)	36 (78.26)	29 (80.56)	0.47
Age, years	43.93 ± 11.04	51.11 ± 10.57	0.012
Cirrhosis, n (%)	13 (28.26)	16 (44.44)	0.123
Treatment
ETV, n (%)	12 (26.09)	12 (33.33)	0.22
TDF, n (%)	32 (26.57)	24 (66.67)	0.84
TAF, n (%)	1 (0.02)	0 (0)	0.79
Hospital stay, days	42 (28, 50)	18 (10, 39)	0.004
HBV parameters
HBeAg^+, n (%)	20 (43.48)	10 (27.78)	0.147
HBsAg, IU/mL	3.10 ± 1.68	2.82 ± 1.67	0.589
HBV DNA, IU/mL	5.76 ± 1.54	5.14 ± 2.48	0.192
qHBV RNA, log10 copies/mL	4.44 ± 1.39	3.90 ± 2.35	0.705
MELD score	21.78 ± 4.69	24.39 ± 3.07	0.007
Laboratory results
PT, S	26.69 ± 4.72	29.30 ± 5.47	0.001
INR	2.44 ± 0.55	2.74 ± 0.55	0.001
Alb, g/L	30.79 ± 4.02	31.10 ± 3.74	0.28
TBil, mg/dL	15.02 (4.30, 29.51)	18.69 (6.93, 27.65)	0.001
ALT, U/L	401.28 (34.28, 1923.58)	438.51 (66.72, 2068.17)	0.79
AST, U/L	365.27 (65.28, 1744.29)	313.44 (29.36, 1697.41)	0.47
Scr, mg/dL	0.64 (0.47, 1.43)	0.57 (0.48, 0.99)	0.25
WBC,10^^9/L	5.17 (4.42, 8.46)	7.92 (5.93, 9.58)	0.38
Ne,10^^9/L	4.40 (2.89, 6.32)	6.07 (4.18, 7.36)	0.015
Plt,10^^9/L	95 (74, 137)	89 (60, 132)	0.69
Lym,10^^9/L	1.06 (0.48, 1.39)	0.81 (0.25, 1.27)	0.001