Review Article

Neutrophil to Lymphocyte Ratio and Spontaneous Bacterial Peritonitis among Cirrhotic Patients: A Systematic Review and Meta-analysis

Table 1

General characteristics of included studies.

First authorYearCountryDesignEnd pointNLR cutoff pointSensitivitySpecificityCasesControlsNOS score
NNLRNNLR

Kwon [21]2015South KoreaRetrospectiveInfection588.30 ± 10.101264.90 ± 6.807

Cai [18]2017ChinaRetrospectiveInfection7087.70 ± 5.0013582.49 ± 1.488

Iliaz [19]2018TurkeyProspectiveSBP9.278%76%7010.20 ± 10.40554.10 ± 3.106

Moreau [24]2018BelgiumRetrospectiveInfection4517.33 ± 15.31639.66 ± 8.347

Mousa [25]2018EgyptProspectiveSBP2.8980%89%1265.46 ± 4.12542.10 ± 0.767

Abdel-Razik [14]2019EgyptRetrospectiveSBP2.5087%80%842.40 ± 1.805981.90 ± 1.207

Awad [15]2020EgyptProspectiveSBP3.50100%43%7026.34 ± 72.67705.65 ± 3.806

Badawi [16]2020EgyptProspectiveSBP3.5355%40%225.96 ± 6.15154.42 ± 2.376

Piotrowski [26]2020PolandRetrospectiveInfection3.9643%86%603.30 ± 3.451492.05 ± 1.286

Baweja [17]2021IndiaProspectiveSBP3.3894%80%506.73 ± 2.70502.81 ± 1.066

Magalhaes [22]2021PortugalRetrospectiveInfection434.80 ± 1.92964.00 ± 2.077

Mani [23]2021GreeceProspectiveSBP630.80 ± 0.09300.68 ± 0.106

Popoiag [27]2021RomaniaRetrospectiveSBP2.4099%82%723.67 ± 1.13144601.87 ± 0.498

Koncoro [20]2022IndonesiaProspectiveInfection207.23 ± 8.46607.36 ± 12.256

N:number; NLR: neutrophil to lymphocyte ratio; SBP: spontaneous bacterial peritonitis; and NOS: the Newcastle–Ottawa quality assessment scale.