Review Article
Neutrophil to Lymphocyte Ratio and Spontaneous Bacterial Peritonitis among Cirrhotic Patients: A Systematic Review and Meta-analysis
Table 1
General characteristics of included studies.
| First author | Year | Country | Design | End point | NLR cutoff point | Sensitivity | Specificity | Cases | Controls | NOS score | N | NLR | N | NLR |
| Kwon [21] | 2015 | South Korea | Retrospective | Infection | — | — | — | 58 | 8.30 ± 10.10 | 126 | 4.90 ± 6.80 | 7 |
| Cai [18] | 2017 | China | Retrospective | Infection | — | — | — | 708 | 7.70 ± 5.00 | 1358 | 2.49 ± 1.48 | 8 |
| Iliaz [19] | 2018 | Turkey | Prospective | SBP | 9.2 | 78% | 76% | 70 | 10.20 ± 10.40 | 55 | 4.10 ± 3.10 | 6 |
| Moreau [24] | 2018 | Belgium | Retrospective | Infection | — | — | — | 45 | 17.33 ± 15.31 | 63 | 9.66 ± 8.34 | 7 |
| Mousa [25] | 2018 | Egypt | Prospective | SBP | 2.89 | 80% | 89% | 126 | 5.46 ± 4.12 | 54 | 2.10 ± 0.76 | 7 |
| Abdel-Razik [14] | 2019 | Egypt | Retrospective | SBP | 2.50 | 87% | 80% | 84 | 2.40 ± 1.80 | 598 | 1.90 ± 1.20 | 7 |
| Awad [15] | 2020 | Egypt | Prospective | SBP | 3.50 | 100% | 43% | 70 | 26.34 ± 72.67 | 70 | 5.65 ± 3.80 | 6 |
| Badawi [16] | 2020 | Egypt | Prospective | SBP | 3.53 | 55% | 40% | 22 | 5.96 ± 6.15 | 15 | 4.42 ± 2.37 | 6 |
| Piotrowski [26] | 2020 | Poland | Retrospective | Infection | 3.96 | 43% | 86% | 60 | 3.30 ± 3.45 | 149 | 2.05 ± 1.28 | 6 |
| Baweja [17] | 2021 | India | Prospective | SBP | 3.38 | 94% | 80% | 50 | 6.73 ± 2.70 | 50 | 2.81 ± 1.06 | 6 |
| Magalhaes [22] | 2021 | Portugal | Retrospective | Infection | — | — | — | 43 | 4.80 ± 1.92 | 96 | 4.00 ± 2.07 | 7 |
| Mani [23] | 2021 | Greece | Prospective | SBP | — | — | — | 63 | 0.80 ± 0.09 | 30 | 0.68 ± 0.10 | 6 |
| Popoiag [27] | 2021 | Romania | Retrospective | SBP | 2.40 | 99% | 82% | 72 | 3.67 ± 1.13 | 14460 | 1.87 ± 0.49 | 8 |
| Koncoro [20] | 2022 | Indonesia | Prospective | Infection | — | — | — | 20 | 7.23 ± 8.46 | 60 | 7.36 ± 12.25 | 6 |
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N:number; NLR: neutrophil to lymphocyte ratio; SBP: spontaneous bacterial peritonitis; and NOS: the Newcastle–Ottawa quality assessment scale.
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