Thrombotic Thrombocytopenic Purpura Associated with the Acquired Immune Deficiency Syndrome
Anand Kumar,1,3Jean Wang,2David Sutton,2and Eric J Bow3
Received24 Apr 1990
Accepted07 Nov 1990
Abstract
A bisexual male presented with acute thrombotic thrombocytopenic purpura (TTP) in association with established acquired immune deficiency syndrome. The patient had classic clinical and laboratory findings of TTP and responded well to plasmapheresis therapy. Previously reported cases of TTP in association with human immunodeficiency virus (HIV) infection are briefly reviewed. Basic concepts in the pathogenesis of TTP are examined in reference to HIV infection.