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Canadian Journal of Infectious Diseases
Volume 6 (1995), Issue 4, Pages 184-190
Case Report

Hantavirus Pulmonary Syndrome: Report of Four Alberta Cases

Ameeta E Singh,1 Denise H Werker,2 Lesia R Boychuk,1 and Lilly J Miedzinski1

1Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada
2British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada

Received 22 March 1995; Accepted 25 March 1995

Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Four Alberta cases of hantavirus pulmonary syndrome are reported. Three cases required intensive care, with one experiencing a fulminant course resulting in death. A fourth case with milder illness was identified after epidemiological investigations. Ribavirin was used in one patient who experienced a successful outcome. A recent open label trial has not supported the efficacy of this drug. The epidemiology of Peromyscus maniculatus, the primary rodent host, and the clinical features of this syndrome are summarized.