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Canadian Journal of Infectious Diseases
Volume 8 (1997), Issue 3, Pages 164-166
Case Report

Short Course Monotherapy with Clarithromycin for Localized Mycobacterium Marinum Skin Infection

Mitchell R Weinstein, Donald E Low, and Tony Mazzulli

Department of Microbiology, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada

Received 21 August 1996; Accepted 4 December 1996

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In vitro studies have shown that Mycobacterium marinum is usually susceptible to clarithromycin. However, there are limited published data on the clinical use of clarithromycin for the treatment of M marinum infections. This report describes a previously healthy 58-year-old man who developed a chronic soft tissue infection of his right hand caused by M marinum. He responded to four weeks’ therapy with clarithromycin. Follow-up at six months showed no relapse. Our experience and review of the literature suggest that short course monotherapy with clarithromycin may be quite effective for uncomplicated soft issue infections caused by M marinum.