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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 18, Issue 2, Pages 149-150
http://dx.doi.org/10.1155/2007/768734
Case Report

Treatment of Candiduria with Micafungin: A Case Series

Danny Lagrotteria,1 Coleman Rotstein,1 and Christine H Lee1,2,3

1Department of Medicine, McMaster University, Canada
2Hamilton Regional Laboratory Medicine Program, McMaster University, Hamilton, Ontario, Canada
3Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

Received 10 May 2006; Accepted 16 November 2006

Copyright © 2007 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

There has been a gradual increase in the incidence of non-Candida albicans-related nosocomial infections. Candida glabrata urinary tract infections have increased in frequency, and treating these infections can be difficult because the organism may be resistant to fluconazole. A newer antifungal agent, micafungin, which belongs in the class of echinocandins, provides an alternative and effective therapy against C glabrata. The present report describes three cases of C glabrata-associated urinary tract infections successfully treated with micafungin. To the authors’ knowledge, this is the first report of successful treatment of C glabrata and azole-resistant C albicans-associated urinary tract infection with an echinocandin.