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Case Report | Open Access
Disseminated Herpes Simplex Virus Type 1 Primary Infection in a Healthy Individual
Guy Boivin
,1,2 Brigitte Malette,3 and Nathalie Goyette11Research Center in Infectious Diseases, Centre Hospitalier Universitaire de Québec, Canada
2Laval University, Québec City, Canada
3Microbiology and Immunology departments of Sainte-Justine Hospital and University of Montréal, Montréal, Quebec, Canada
Abstract
BACKGROUND: Primary herpes simplex virus (HSV) infection usually involves one mucosal region.OBJECTIVE: To describe an unusual disseminated HSV-1 infection involving two mucosal sites in a healthy man.RESULTS: Primary HSV infection involved oral and genital mucosa and was associated with viremia, hepatitis and rash. Phylogenetic analysis of genital and oral viruses revealed that the patient was infected by a single HSV-1 strain.CONCLUSION: Use of polymerase chain reaction detection techniques for HSV may identify viremic patients in the absence of obvious immunosuppression.
Copyright
Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
