Original Article | Open Access
Maxym Choptiany, Lyle Wiebe, Bill Limerick, Pete Sarsfield, Mary Cheang, Bruce Light, Greg Hammond, Kerry MacDonald, Elly Trepman, Peter Pappas, John M Embil, "Risk Factors for Acquisition of Endemic Blastomycosis", Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 20, Article ID 824101, 5 pages, 2009. https://doi.org/10.1155/2009/824101
Risk Factors for Acquisition of Endemic Blastomycosis
BACKGROUND: Blastomycosis is potentially fatal, but environmental risk factors for acquiring blastomycosis are not well established.METHOD: Matched cross-sectional questionnaire of 112 patients with history of blastomycosis and 118 control subjects in Manitoba and northwestern Ontario.RESULTS: The most common tissues involved with blastomycosis were pulmonary, skin and soft tissues, and bone. A significantly greater proportion of patients with blastomycosis than control subjects were involved in outdoor occupations. A significantly greater percentage of patients with blastomycosis were immunosuppressed either from collagen vascular disease or immunosuppressive therapy, or had hypothyroidism. A significant association between canine and human blastomycosis was not observed.CONCLUSIONS: Independent risk factors for development of blastomycosis included immunosuppression for any reason (including drugs or disease), collagen vascular disease, being an outdoor worker, and having a coworker with blastomycosis. Canine blastomycosis was not a risk factor for human disease in dog owners.
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