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Case Report | Open Access
Trichosporon asahii Infection after Total Knee Arthroplasty: A Case Report and Review of the Literature
Qiang Zuo,1,2 Lele Dong,2 Weidong Mu
,1 Lingyun Zhou,3 Tongping Hu,4 and Hua Zhang51Department of Orthopedics, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
2Department of Orthopedics, the First Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia, China
3International Education College, Jiang Xi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province, China
4Clinical Laboratory, the First Affiliated Hospital of Baotou Medical College, China
5Department of Oncology, the Third Affiliated Hospital of Inner Mongolia Medical College, Baotou, Inner Mongolia, China
Abstract
Reports of fungal infection after total knee arthroplasty are extremely rare. In most reports, the infecting organism is a Candida species. The present report describes a case involving a 73-year-old immunocompetent woman who underwent total knee arthroplasty and presented one month later with signs of prosthetic infection. She underwent joint debridement and the fluid was sent for culture and sensitivity testing. The culture showed growth of Trichosporon asahii. The patient was administered intravenous and intra-articular injections of amphotericin B, followed by antifungal treatment with voriconazole for one year. At 26 months of follow-up, there was no evidence of infection and the patient was ambulating with a walker. To the authors’ knowledge, the present case is the first report of T asahii infection following knee replacement. Early detection, prompt institution of the appropriate antibiotics and regular follow-up are recommended.
Copyright
Copyright © 2015 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
