Evaluation of Risk Factors for Antibiotic Resistance in Patients with Nosocomial Infections Caused by Pseudomonas aeruginosa

Table 4

Independent risk factors associated with the perspective antimicrobial resistances in resistant to antipseudomonal antibiotics related to nosocomial P. aeruginosa infections.

Variables	Adjusted OR (95% CI)
Resistance to imipenem
Prior receipt of cefazolin	3.33 (1.11–10.0)	0.03
Resistance to meropenem
History of cerebrovascular disease	3.57 (1.31–9.76)	0.01
Prior receipt of meropenem	4.13 (1.21–14.07)	0.02
Resistance to piperacillin-tazobactam
Stay at neurology intensive care unit	4.47 (1.69–11.84)	0.003
Resistance to ciprofloxacin
Stay at neurology intensive care unit	4.24 (1.5–11.98)	0.006
Mechanic ventilation	11.7 (2.24–61.45)	0.004
Resistance to amikacin
Intensive care unit stay > 60 days	7.27 (1.60–33.02)	0.01
Thoracotomy tube	3.41 (1.03–11.24)	0.04
Resistance to ceftazidime
Stay at neurology intensive care unit	5.07 (1.92–13.34)	0.001