Genomic Analysis of a Serotype 5<i> Streptococcus pneumoniae</i> Outbreak in British Columbia, Canada, 2005–2009

<div>Quarterly prevalence of serotype 5 pneumococcal IPD in British Columbia. Numbers above bars are % serotype 5 isolates per quarter. <svg height="6.01072pt" id="M3" style="vertical-align:-0.04980993pt" version="1.1" viewbox="-0.0498162 -5.96091 7.75925 6.01072" width="7.75925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M471 153C471 170 463 194 452 212C400 220 373 229 322 255C373 281 400 290 452 298C463 316 471 339 471 357C456 366 431 371 410 370C377 329 356 310 308 279C311 336 317 364 336 413C326 432 310 451 294 459C279 451 262 432 252 413C271 364 277 336 280 279C232 310 211 329 178 370C157 371 132 367 117 357C117 340 125 316 136 298C188 290 215 281 266 255C215 229 188 220 136 212C125 194 117 171 117 153C132 144 157 139 178 140C211 181 232 200 280 231C277 174 271 146 252 97C262 78 278 59 294 51C309 59 326 78 336 97C317 146 311 174 308 231C356 200 377 181 410 140C431 139 456 143 471 153Z" id="g113-43"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g></svg> is introduction of PCV13; <svg height="9.10327pt" id="M4" style="vertical-align:-3.12932pt" version="1.1" viewbox="-0.0498162 -5.97395 6.81973 9.10327" width="6.81973pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M515 -240V-213C445 -206 438 -202 438 -132V332C438 399 440 418 441 439L437 442C421 434 408 431 402 431C394 430 389 431 375 435C363 440 342 445 306 449C168 450 38 341 38 197C38 101 108 -12 253 -12L359 30V-130C359 -201 353 -207 274 -213V-240H515ZM359 60C340 51 316 44 285 44C211 44 128 109 128 230C128 348 194 408 262 408C294 408 336 392 359 366V60Z" id="g121-111"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="511" vert-adv-y="511"></glyph.data></g></svg>: quarterly (i.e., three-month period).</div>

Canadian Journal of Infectious Diseases and Medical Microbiology

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Figure 1

Figure 1: Genomic Analysis of a Serotype 5<i> Streptococcus pneumoniae</i> Outbreak in British Columbia, Canada, 2005–2009 

Canadian Journal of Infectious Diseases and Medical Microbiology

Genomic Analysis of a Serotype 5 Streptococcus pneumoniae Outbreak in British Columbia, Canada, 2005–2009

Figure 1