Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region

Table 2

Antimicrobial susceptibility of C. difficile present in British Columbia in 2008 (µg/mL).

	Metronidazole	Vancomycin	Clindamycin
Susceptible number (%)	341 (100)	341 (100)	107 (31.4)
Intermediate number (%)	0 (0)	NA	89 (26.1)
Resistant number (%)	0 (0)	0 (0)	145 (42.5)
MIC range	0.016–4.0	0.125–2.0	0.25–>256
MIC mean	0.26	0.56	42.0
^†MIC90	0.50	1.0	>256

Where MIC was unknown (>256 µg/mL observations), 256 µg/mL was used to calculate the mean.
MIC required to inhibit 90% of organisms.
MIC: minimum inhibitory concentration.