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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 2016, Article ID 8594107, 7 pages
Research Article

High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion

1Hepatology and Cancer Biotherapy Ward, Beijing You’an Hospital, Capital Medical University, Beijing, China
2State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
3Network Information Center, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

Received 27 March 2016; Revised 4 July 2016; Accepted 21 July 2016

Academic Editor: Roshanak Tolouei Semnani

Copyright © 2016 Yachao Qu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

We have also do some research on T cell functional assays. Compared with the baseline, the percentage of Cytotoxic T lymphocytes(CTL) has been increased after HBeAg seroconversion which demonstrated the CTL play an important role in the treatment of HBV. The results of percentage of CTL in the patient 2 and 3 before and after HBeAg seroconversion are shown in Supplement data.

  1. Supplementary Material