High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion

Table 2

The number of raw sequencing reads and the rearranged TRBV_J clones.

Samples	Raw reads	Average length (bp)	TRBV_J gene pairing	TRBV-only gene	TRBJ-only gene	Nonhomologous
P1_pre	526,527	256	122,007	256,443	33,484	69,906
P1_post	526,527	224	97,239	263,323	60,92	87,755
P2_pre	685,596	233	119,794	252,164	59,132	129,358
P2_post	685,596	228	150,460	332,818	83,253	106,459
P3_pre	607,994	216	169,465	228,845	79,726	96,378
P3_post	607,994	236	181,292	231,489	73,901	82,747
P4_pre	370,210	242	101,415	181,392	39,651	37,718
P4_post	370,210	232	251,846	37,457	35,291	27,889

The reads used for analyses were adjusted from the raw sequencing data to guarantee that each patient has the same sample size in both pre- and posttreatments.
TRBV: TCR beta chain variable gene; TRBJ: TCR beta chain junction gene.