Research Article

First Insight into a Nationwide Genotypic Diversity of Mycobacterium tuberculosis among Previously Treated Pulmonary Tuberculosis Cases in Benin, West Africa

Table 1

Resistance pattern of strains to first-line drugs.

Type of resistanceFailure
(n = 24)
n (%)
Relapse
(n = 71)
n (%)
Default
(n = 5)
n (%)
Total
(n = 100)
n (%)

Susceptible to all drugs12 (50.0)45 (63.4)3 (60.0)60 (60.0)
Monoresistance
 H1 (4.2)1 (1.4)0 (0.0)2 (2.0)
 S3 (12.5)10 (14.1)1 (20.0)14 (14.0)
 R0 (0.0)0 (0.0)1 (20.0)1 (1.0)
 E1 (4.2)1 (1.4)0 (0.0)2 (2.0)
 Total5 (20.8)12 (16.9)2 (40.0)19 (19.0)
Multidrug resistance
 HR0 (0.0)2 (2.8)0 (0.0)2 (2.0)
 HRE1 (4.2)1 (1.4)0 (0.0)2 (2.0)
 HRS1 (4.2)1 (1.4)0 (0.0)2 (2.0)
 HRES3 (12.5)3 (4.2)0 (0.0)6 (6.0)
 Total5 (20.8)7 (9.9)0 (0.0)12 (12.0)
Other patterns
 HS1 (4.2)1 (1.4)0 (0.0)2 (2.0)
 HSE0 (0.0)2 (2.8)0 (0.0)2 (2.0)
 RS0 (0.0)1 (1.4)0 (0.0)1 (1.0)
 ES1 (4.2)3 (4.2)0 (0.0)4 (4.0)
 Total2 (8.3)7 (9.9)0 (0.0)9 (9.0)

H: isoniazid; E: ethambutol; S: streptomycin; R: rifampicin.