In Vitro Activity of Iclaprim against Methicillin-Resistant Staphylococcus aureus Nonsusceptible to Daptomycin, Linezolid, or Vancomycin: A Pilot Study

Table 1

Iclaprim in vitro activity against MRSA isolates nonsusceptible to daptomycin, linezolid, or vancomycin.

MRSA phenotype (number)	Iclaprim MIC ≤ 1, µg/mL (%)	Iclaprim MIC50/MIC90 (µg/mL)	MIC range (µg/ml)
Daptomycin nonsusceptible (n = 7)	5/7 (71.4)	0.25/>8	0.12–>8
Linezolid nonsusceptible (n = 26)	26/26 (100.0)	0.06/0.25	0.03–1
Vancomycin intermediate (n = 23)	16/23 (69.6)	0.25/>8	0.25–>8
Vancomycin resistant (n = 5)	3/5 (60.0)	0.5/>8	0.25–>8