Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study

Table 4

Characteristics of antimicrobial treatment.

Characteristics	Initial treatment		Further treatment
	Number	%	Number	%
(i) Delay of introduction:
(a) <24 h	42	98%	—	—
(b) 24 h ≪ 48 h	0	0%	—	—
(c) >48 h	1	2%	—	—
(ii) Type of prescription:
(a) Not specifically adapted	22	51%	—	—
(b) Probabilistic	20	46,5%	7	41%
(c) Documented	1	2,5%	10	59%
(iii) Type of treatment:
(a) Monotherapy	18	43%	3	18%
(b) Association	25	57%	14	82%
(iv) Average length of initial treatment: (mean +/− SD)	4,2 +/− 0,6		—
(v) Adequacy of treatment:
(a) Adequate	31	72%	16	93
(b) Inadequate	12	28%	1	7%
(vi) Effectiveness:
(a) Efficient	27	63%	6	35%
(b) Ineffective	16	37%	11	65%
(vii) Initial treatment modification reason:
(a) Escalation	—	—	4	21%
(b) Deescalation	—	—	13	79%
(viii) Most prescribed family:
(a) Beta-lactams	12	28%	3	18%
(b) Polymyxins	8	18,7%	—	—
(c) Beta-lactams + aminoglycoside	8	18,7%	1	6%
(d) Beta-lactams + polymyxins	6	14%	8	47%
(ix) The most commonly used antibiotics:
(a) Imipenem	9	21,4%	8	45,5%
(b) Colistin	12	27%	4	23,3%
(c) Amikacin	28	12,1%	2	9,1%
(d) Vancomycin	22	9,4%	2	9,1%
(x) Cost of treatment:
(a) Total cost per patients	899,27 Euros [259,85–1544,69]
(b) Daily cost per patients	31,01 Euros [17,48–54,59]