Pathogenicity of Virulent Species of Group C Streptococci in Human

Table 2

Virulence factors and morbidity against human of group C streptococci.

Species	Virulence factors	Disease	Origin	References
S. equi subs. equi	Protein	Septic arthritis, meningitis	Animals, human	[1, 6, 11]
S. equi subs. zooepidemicus	Surface-exposed protein (Szp)	Meningitis, bacteremia, endocarditis	Unpasteurized milk; animals	[6, 9, 11]
S. equi subs. zooepidemicus; S. dysgalactiae subs. equisimilis	Surface-exposed protein (Szp); emm gene homologs, streptokinase, streptolysin O and S, M protein, hemolysin, C5a peptidase, glyceraldehyde 3-phosphate dehydrogenase (GAPDH), hyaluronidase	Pharyngitis, pneumonia, endocarditis, meningitis, acute glomerulonephritis, skin and soft tissue infections, septic arthritis, osteomyelitis, endometritis, streptococcal toxic shock-like syndrome, necrotizing fasciitis, cellulitis, septic arthritis, bacteremia, ,	Unpasteurized dairy products, animals, human	[2, 5, 7, 9–11, 13]

: rheumatic fever.
: rheumatic heart disease.