Canadian Journal of Infectious Diseases and Medical Microbiology

Research Article

Isolation of Extended-Spectrum β-lactamase- (ESBL-) Producing Escherichia coli and Klebsiella pneumoniae from Patients with Community-Onset Urinary Tract Infections in Jimma University Specialized Hospital, Southwest Ethiopia

Table 3

Resistance profiles of ESBL-producing and non-ESBL-producing Escherichia coli and Klebsiella pneumoniae isolates in JUSH, Southwest of Ethiopia.


Antibiotics	Total R (N%)	ESBL-positive (n = 17) (N%)		ESBL-negative (n = 57) (N%)		value
Antibiotics	R	R	S	R	S	value

Cefotaxime	18 (24.3%)	17 (100%)	0	1(1.8%)	56 (98.2%)	0.001
Ceftriaxone	17 (23.0%)	17 (100%)	0	0	57 (100%)	0.001
Ceftazidime	16 (21.6%)	12 (70.6%)	5 (29.4%)	4 (7.0%)	53 (93.0%)	0.001
AMC	27 (36.5%)	14 (82.4%)	3 (17.6%)	13 (22.8%)	44 (77.2%)	0.001
Cephalothin	53 (71.6%)	17 (100%)	0	36 (63.2%)	21 (36.8%)	0.051
Ampicillin	74 (100%)	17 (100%)	0	57 (100%)	0	—
Gentamicin	17 (23%)	11 (64.7%)	6 (35.3%)	6 (10.5%)	51(89.5%)	0.001
Amikacin	7 (9.5%)	4 (23.5%)	13 (76.5%)	3 (5.3%)	54 (94.7%)	0.024
NA	38 (51.4%)	13 (76.5%)	4 (23.5%)	25 (43.9%)	32 (56.1%)	0.001
CIP	24 (32.4%)	13 (76.5%)	4 (23.5%)	11 (19.3%)	46 (80.7%)	0.001
Norfloxacin	23 (31.1%)	13 (76.5%)	4 (23.5%)	10 (17.5%)	47 (82.5%)	0.001
SXT	41 (55.4%)	14 (82.4%)	3(17.6%)	27 (47.4%)	30 (52.6%)	0.001
Tetracycline	45 (60.8%)	14 (82.4%)	3 (17.6%)	31 (54.4%)	26 (45.6%)	0.021
C	30 (40.5%)	12 (70.6%)	5 (29.4%)	18 (31.6%)	39 (68.4%)	0.004
Imipenem	0	0	17 (100%)	0	57 (100%)	—

R: resistant, S: sensitive, AMC: amoxicillin-clavulanic acid, NA: nalidixic acid, CIP: ciprofloxacin, SXT: trimethoprim-sulfamethoxazole, C: chloramphenicol.