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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 2019, Article ID 3270393, 5 pages
https://doi.org/10.1155/2019/3270393
Research Article

Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy

1Department of Laboratory Medicine, Shanxi Provincial People’s Hospital, Taiyuan, China
2Department of Tuberculosis, The Fifth People’s Hospital of Taiyuan, Taiyuan, China
3Department of Laboratory Medicine, Children’s Hospital of Shanxi Province, Taiyuan, China

Correspondence should be addressed to Xian-hui Zhang; moc.361@87iuhnaixgnahz

Received 21 January 2019; Accepted 8 May 2019; Published 27 May 2019

Academic Editor: Lucia Lopalco

Copyright © 2019 Wei Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. Methods. All data were collected from the clinical database of The Fifth People’s Hospital of Taiyuan, China. A total of 151 patients who had newly diagnosed active tuberculosis with tuberculosis therapy in hospital and 129 healthy controls were selected. Results. Median ratio of monocytes to lymphocytes was 0.45 (IQR: 0.28–0.67) in patients before treatment and 0.32 (IQR: 0.25–0.46) on discharge (). Conclusions. Ratio of monocytes to lymphocytes may be applied in diagnosis and the chemotherapeutic efficacy of active tuberculosis.