Canadian Journal of Infectious Diseases and Medical Microbiology / 2019 / Article / Tab 3 / Research Article
Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β -Lactamase- and AmpC β -Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi Arabia Table 3 Antibiotic resistance patterns of Gram-negative bacteria producing ESBLs and AmpC β -lactamases compared to nonproducer isolates.
Antibiotic Total number of Gram-negative rods (n = 311) valueTotal number of Gram-negative rods (n = 311) valueNon-ESBL (n = 227) ESBL (n = 84) AmpC (n = 101) Non-AmpC (n = 210) Amikacin 31 (36.9) 61(26.9) 0.085 57 (56.4) 35 (16.7) <0.001 Tobramycin 50 (42) 92 (40.5) 0.134 67 (66.3) 67 (31.9) <0.001 Gentamicin 40 (47.6) 81 (35.7) 0.055 66 (65.3) 55 (26.2) <0.001 Amoxicillin/clavulanate 58 (69) 91 (40.1) <0.001 93 (92.1) 56 (26.7) <0.001 Cefuroxime 81 (96.4) 137 (60.4) <0.001 92 (91.1) 126 (60) <0.001 Ceftazidime 72 (85.7) 76 (33.5) <0.001 65 (64.4) 83 (39.5) <0.001 Cefotaxime 78 (92.9) 85 (37.4) <0.001 76 (75.2) 87 (41.4) <0.001 Cefepime 75 (89.3) 87 (38.3) <0.001 75 (74.3) 87 (41.4) <0.001 Meropenem 24 (28.6) 59 (26.0) 0.755 50 (49.5) 33 (15.7) <0.001 Piperacillin 53 (63.1) 77 (33.9) <0.001 72 (71.3) 58 (27.6) <0.001 Piperacillin/tazobactam 42 (50) 77 (33.9) 0.010 65 (64.4) 54 (25.7) <0.001 Imipenem 26 (31) 62 (27.3) 0.527 58 (57.4) 30 (14.3) <0.001 Aztreonam 69 (82.1) 98 (43.2) <0.001 82 (81.2) 85 (40.5) <0.001 Ciprofloxacin 51 (60.7) 92 (40.5) 0.002 74 (73.3) 69 (32.9) <0.001 Ofloxacin 50 (59.5) 91 (40.1) 0.002 70 (69.3) 71 (33.8) <0.001 Nitrofurantoin 50 (59.5) 103 (45.4) 0.027 78 (77.2) 75 (35.7) <0.001 Trimethoprim/sulfamethoxazole 76 (90.5) 140 (61.7) <0.001 91 (90.1) 125 (59.5) <0.001 Colistin 4 (4.8) 5 (2.2) 0232 7 (6.9) 2(1.0) 0.003