Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of the Literature

Table 3

Treatment and outcome of histoplasmosis-associated HLH patients at our institution (n = 5).

Case #	Antifungal drug	HLH specific treatment	Outcome (hospital discharge)
1	Liposomal amphotericin B for 2 weeks, then itraconazole for 12 months	None	Survived
2	Liposomal amphotericin B for 4 weeks, then oral azoles for 4 years	Dexamethasone 10 mg/m^2 for 2 days	Survived
3	Voriconazole PO (discharged to hospice, patient preference)	None	Discharged to hospice
4	Liposomal amphotericin B for 2 weeks then itraconazole for 4 months	Dexamethasone 10 mg/m^2	Survived
5	Liposomal amphotericin B for 2 weeks then oral azoles	None	Died (day 43)

Notes. BM: bone marrow, IL: interleukin, N/A: not applicable.